IFNL3

該基因編碼一種與I型幹擾素和IL-10傢族有遠親關系的細胞因子。這個基因，白細胞介素28a（il28a）和白細胞介素29（il29）是三個密切相關的細胞因子基因，它們在一個定位於19q13的染色體區域上形成一個細胞因子基因簇。病毒感染可誘導這三個基因所編碼的細胞因子的表達。這三種細胞因子都與一種異二聚體ii類細胞因子受體相互作用，後者由白細胞介素10受體β（il10rb）和白細胞介素28受體α（il28ra）組成。[由RefSeq提供，2008年7月]
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]